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Jigsaw:"Oh yes, there will be blood."

Rigg:"You need to start thinking outside the box, or his son is going to end up in one."

Jigsaw:"I don't intend to mock you officer, but I'm a cancer patient. How could you possibly put in anymore pain than I'm already in?"

Gus:"How do you just wake up in a room and have no idea where you are?"
Xavier:"I guess you've never been drunk before."
Gus:"I've been drunk, I spent 3 years in college. Drunk? This isn't drunk, this is kidnapping."

Jigsaw:"I want to play a game."

Amanda Young:"Gameover."

Jigsaw:"Greetings and welcome. I trust that you are all wondering where you are. I can assure you that while your location is not important, what these walls offer for you is important. Salvation, if you earn it. Three hours from now the door to this house will open. Unfortunately, you only have 2 hours to live. Right now, you are breathing in a deadly nerve agent. You've been breathing it since you've arrived here. Those of you familiar with the Tokyo subway attacks will know its devastating effects on the human body. The only way to overcome it and walk out that door is to find an antidote. Several are hidden around this house. One is inside the safe in front of you. You all posses the combination to the safe. Think hard. The numbers are in the back of your mind. The clue to their order can be found 'over the rainbow'. Once you realize what you all have in common, you will gain a better understanding of why you're here. X marks the spot for that clue, so look carefully. Let the game begin."

Addison:"What is this? House arrest?"

Jigsaw:"We haven't been properly introduced. My name is John."
Detective Eric Matthews:"I thought you liked to be called Jigsaw."
Jigsaw:"No, it was the police and the press that coined the nickname 'Jigsaw'. I never encouraged or claimed that. The jigsaw piece I cut from my subjects was only ever meant to be a symbol that that subject was missing something. A vital piece of the human puzzle. The survival instinct."

Obi:"If you're going to threaten me with a knife, you may as well cut me a little."

Jigsaw:"Hello Michael, I want to play a game. So far in what could loosely be called your life you've made a living watching others. Society would call you an informant, a rat, a snitch. I call you unworthy of the body you possess, of the life that you've been given. Now we will see if you are willing to look inward rather than outward to give up the one thing you rely on in order to go on living. The device around your neck is a death mask. The mask is on a spring timer. If you do not locate the key in time the mask will close. Think of it like a Venus Flytrap. What you are looking at right now is your own body not more than two hours ago. Don't worry, you're sound asleep and can't feel a thing. Taking into account that you are at a great disadvantage here I'm going to give you a hint as to where I've hidden the key, so listen carefully. The hint is this, It's right before your eyes. How much blood will you shed to stay alive, Michael? Live or die, make your choice."

Jigsaw:"Hello Obi, I want to play a game. For years you have burned those around you with your lies, cons, and deceits. Now you will have a chance to redeem yourself, for the games you've played with others, by playing one of mine. Inside the device in front of you are two antidotes for the poison coursing through your veins. One is my gift to you for helping me kidnap the others, the second is yours to donate. However, one of them will come with a price. Remember Obi, once you're in Hell, only the devil can help you out."

Jigsaw's puppet laugh

Amanda Young:"If it's stuck, it's a trap."
Xavier:"Lady, this whole house is a trap!"

Detective Eric Matthews:"Where is he?!"
Jigsaw:"Where is he? That's a problem you're going to have to solve before it's too late. He has about, two hours, until the gas creeping into his nervous system begins to break down his body tissue, and he begins to bleed from every orifice he has. Oh yes, there will be blood."

Jigsaw:"Hello, Xavier, I want to play a game. The game I want to play is very similar to the one you've been playing as a drug dealer. The game of offering hope to the desperate for a price. I think we can agree that your situation is desperate, so I'm offer you hope. The price you pay is that you must crawl into the same pit of squalor you force your customers into. By entering this room, a timer has been started. When the timer expires the door in front of you will be locked forever. Only in finding the key, before the timer runs out, can you unlock it and retrieve the antidote inside. I will give you just one hint as to where that key is. It will be like finding a needle in a haystack. Let the game begin."